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产品目录

重组人IL-36γ,152a.a.图片
产品货号:
GS4858
中文名称:
重组人IL-36γ,152a.a.
英文名称:
Recombinant Human Interleukin-36 gamma, 152a.a.
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 17.0kDa,a single non-glycosylated polypeptide chain containing 152 amino acids.
储存条件:冷冻(-20℃)

概述

Interleukin-36(IL-36)is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases.IL-36α,IL-36β,and IL-36γ(formerly IL-1F6,IL-1F8,and IL-1F9)are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2(IL-1RL2)and IL-1RAcP.IL-36γ is secreted when transfected into 293-T cells and it could constitute part of an independent signaling system analogous to interleukin-1 alpha(IL-1A),beta(IL-1B)receptor agonist and interleukin-1 receptor type I(IL-1R1).Furthermore,IL-36γ also can function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2.Human IL-36γ(152a.a)shares 58%,59%,68%and 69%a.a.sequence identity with mouse,rat,bovine and equine IL-36γ,respectively,and 23 - 57%a.a.sequence identity with other family members.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>95%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The ED50 as determined by its ability to induce IL-8 secretion by human preadipocytes is less than 10ng/ml,corresponding to a specific activity of>1×105 IU/mg.
成分Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素Less than 1 EU/μg of rHuIL-36γ,152a.a.as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND

相关搜索:重组人IL-36γ,152a.a.IL-36γ, 152a.a., HumanRecombinant Human Interleukin-36 gamma, 152a.a.
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